Ganmaa et al. (Harvard researcher)
Abstract
BACKGROUND:
Nutrients, hormones and growth factors in dairy foods may stimulate growth hormone (GH), insulin-like growth factor I (IGF-I), and raise the ratio of IGF-I to its binding protein, IGFBP-3. We conducted pilot studies in Mongolia and Massachusetts to test the extent to which milk intake raised somatotropic hormone concentrations in prepubertal children.
METHODS:
In Ulaanbaatar, we compared plasma levels before and after introducing 710 ml daily whole milk for a month among 46 10-11 year old schoolchildren. In a randomized cross-over study in Boston, we compared plasma hormone levels of 28 6-8 year old girls after one week of drinking 710 ml low fat (2%) milk with their hormone levels after one week of consuming a macronutrient substitute for milk.
RESULTS:
After a month of drinking whole milk, Mongolian children had higher mean plasma levels of IGF-I (p < 0.0001), IGF-I/IGFBP-3 (p < 0.0001), and 75th percentile of GH levels (p = 0.005). After a week of drinking low fat milk, Boston girls had small and non-significant increases in IGF-1, IGF-1/IGFBP-3 and GH.
CONCLUSION:
Milk drinking may cause increases in somatotropic hormone levels of prepubertal girls and boys. The finding that milk intake may raise GH levels is novel, and suggests that nutrients or bioactive factors in milk may stimulate endogenous GH production.
Maruyama et al.
Abstract
BACKGROUND:
Modern genetically improved dairy cows continue to lactate throughout almost the entire pregnancy. Therefore, recent commercial cow's milk contains large amounts of estrogens and progesterone. With regard to the exposure of prepubertal children to exogenous estrogens, the authors are particularly concerned about commercial milk produced from pregnant cows. The purpose of the present study was therefore to examine concentrations of serum and urine sex hormones after the intake of cow milk.
METHODS:
Subjects were seven men, six prepubertal children, and five women. The men and children drank 600 mL/m(2) of cow milk. Urine samples were collected 1 h before the milk intake and four times every hour after intake. In men the serum samples were obtained before and 15, 30, 45, 60, 90 and 120 min after milk intake. Women drank 500 mL of cow's milk every night for 21 days beginning on the first day of the second menstruation. In three successive menstrual cycles, the day of ovulation was examined using an ovulation checker.
RESULTS:
After the intake of cow milk, serum estrone (E1) and progesterone concentrations significantly increased, and serum luteinizing hormone, follicle-stimulating hormone and testosterone significantly decreased in men. Urine concentrations of E1, estradiol, estriol and pregnanediol significantly increased in all adults and children. In four out of five women, ovulation occurred during the milk intake, and the timing of ovulation was similar among the three menstrual cycles.
CONCLUSIONS:
The present data on men and children indicate that estrogens in milk were absorbed, and gonadotropin secretion was suppressed, followed by a decrease in testosterone secretion. Sexual maturation of prepubertal children could be affected by the ordinary intake of cow milk.
Milk cortisol concentrations as an indicator of stress in lactating dairy cows
Abstract
The aim of this study was to compare cortisol concentrations in plasma (PCC) and milk (MCC) following administration of exogenous ACTH1-24 or activation of the hypothalamo-pituitary-adrenal axis by a stressor (transport) in cows. Fifteen cows in mid-lactation were assigned to treatments with ACTH1-24 (0.05 mg SynacthenTM iv at 1300h), transport (trucking for two 45 min periods from 1300h) or control (sampling only) in a 3x3 Latin square design. Blood samples were collected hourly from 1300- 1500h and a composite milk sample was obtained at routine milking at 1515h. There was a 6-fold elevation in PCC by 60 min following both ACTH treatment and transportation. At 120 min, PCC was two-fold higher in ACTH treated cows but remained at levels similar to those at 60 min in the transported animals, indicating that the adrenocortical response had been maintained during transport. Mean MCC was 12-fold greater after the transport treatment and a factor of 2 higher after ACTH treatment, compared to the control treatment (P<0.01). Values of MCC and PCC at the 120 min sampling were highly correlated (r = 0.80; P<0.001). This suggested that MCC may be a useful indicator of adrenocortical response to stressors, provided samples are obtained during the period of elevated PCC.
Some other websites to round out my hypothesis:
Growth hormones in milk: myth/fact
Turns Out Your "Hormone-Free" Milk Is Full of Sex Hormones
Chickens do not receive growth hormones so why all the confusion?
Natural occurrence of steroid hormones in food
What's in your milk?
that job for !INTP","you will do no good" and how many don't accepted/succeed because of non skill related reason?
