I recognize three levels of this in myself. Level 2 includes Level 1, and Level 3 includes Level 2.
Level 1 happens after a weekday of school -- talking to people in a quiet environment, listening to lectures, taking notes for 3-6 hours. My eyes itch, my head hurts/feels compressed, I lack interest to discuss most non-concrete things, I tend to crave a cigarette or two.
Level 2 happens during/after non-school socializing -- a party I'm forced to attend or host, most often (I attend/host no parties of my own volition). I get the urge to move my legs à la Restless Leg Syndrome, sounds and lights can be physically painful, my body feels cold, I move my hands a lot and do not know what to do with them, pulsing headaches manifest.
Level 3 occurs only when I've slept poorly and/or been doing very mentally demanding work for several days in a row (like finals week). I become paranoid, I see phosphene-like lights even while my eyes are open, I crave to outright abuse caffeine and nicotine, my chest muscles twitch, breathing becomes unalterably shallow, my upper back becomes tense, I get cramps in my calves, I walk on the tips of my toes. Music, food and most conversations become very unpleasant. I've been told I look very funny like this.
Symptoms go away after reading on the computer (I can't read books when tired), playing with (simple) videogames, taking a long bath, jogging, and/or meditating.