INTPs don't often care for social norms created and maintained by the Nurse Ratched-types who usually define terms like "substance abuse" and socially acceptable weights. INTPs are likely to see the norms as somewhat arbitrary, and then disregard them in favor of "doing their own thing", as it were, whether overindulging or abstaining completely. Unfortunately for INTPs, "substance abusive" behavior ends up looking like "behavior outside of the norm", which is more or less a specialty for the INTP. Essentially, "odd" behavior gets defined as "bad" behavior, which works to the disadvantage of the INTP.
Consider alcohol: some of the signs of "alcohol abuse" are 1) drinking alone, 2) using alcohol as a "social crutch" and 3) being drunk at inappropriate times. (There are other signs of alcoholism, but let's focus on these.)
To an INTP, the first two rules look like the worst excesses of Extraverted Sensors. "Drinking alone", for instance, could only be healthily done by people who a) don't ALWAYS need to be around other people to enjoy himself and b) don't really consider unorthodox behavior necessarily "bad". Of course, an Extraverted Sensor would think there was an inherent problem with drinking alone because what kind of weirdo could possibly enjoy his own company and engage in behavior that was so unspeakably outside the norm, right? Or, in the second case, what kind of social misfit could possibly want a buzz to enjoy the pleasures of a party full of strangers (an INTX, that's who! Gets no energy being around people, wants to let "N" run amok!) Whether or not an INTP actually does this, they can see the illogical banality of these indicators, and shrug their shoulders because the INTP lives in a world of Extraverted Sensors who enjoy telling people what to do and, ultimately, do not understand what drives INTP behavior.
In the third instance, again, the INTP must surely see this as a rule made by Sensors. "Inappropriate times" really has no meaning outside of social rules of decorum, which the INTP may or may not obey but won't let get in the way of a good "experiment". An athletic INTP might, for instance, take the soccer or football field after having consumed 7 or 8 drinks, just to see precisely the diminished quality of their athletic performance. According to the letter of the rule, an athletic event would be an "inappropriate time" to be drunk, but an INTP can see the value in this experiment as a guage of both a) the effects of drinking on performance and b) as a personal measure of athletic ability. But in a Sensor world, this is an indicator of "alcohol abuse" without reference to the INTPs "Super T" need to experiment and analyze and know the world and himself.
Bottom line: all rules, to some extent, take "odd" behavior and define it as "bad" behavior, and you'll find INTPs in every category of "odd" behavior whether it's "bad" in any meaningful way: this is just one more iteration.