has anyone here taken a personal genome test? Scientist have found a gene related to introversion.

[deadpixel]

Scientist have found A specific gene linked to introversion, The Gene is called RGS2, and even more specifically a variant of it called rs4606. If you have done genome testing with 23andme or any other genome testing, would you please be so kind as to do a search for RGS2 in your raw data input to see if you have the gene RGS2 with the varation rs4606.

Markers spanning RGS2 were associated with childhood behavioral inhibition, a temperamental precursor of social anxiety disorder (haplotype P = 3 x 10(-5); odds ratio, 2.99 in complete trios). In independent samples, RGS2 markers, including rs4606, which has previously been associated with RGS2 expression, were also associated with introversion (a core personality trait in social anxiety disorder) and with increased limbic activation (insular cortex and amygdala) during emotion processing (brain phenotypes correlated with social anxiety). The genotype at rs4606 explained 10% to 15% of the variance in amygdala and insular cortex activation to emotional faces.
As soon as I read this information I searched for it in my raw input and I do indeed have the rs4606 variation.

 

[Ribald]

Very interesting. Sounds like a huge blow to free will, too. Wish I could contribute my genomic info, but I haven't had it tested yet. Will when I get the money.

 

[deadpixel]

I have a SEVERE case of social anxiety, this explains a lot for me. The test was only $99, idk how much it is now.

 

[peoplesuck]

if you look up "is introversion nature or nurture" you will get mixed results and i dont know why..we have evidence!

 

[deadpixel]

if you look up "is introversion nature or nurture" you will get mixed results and i dont know why..we have evidence!

I just know that im introverted and have social anxiety, I wondered if there was a reason why and discovered a specific SNP in my genes seem to be very relevant to introversion and social anxiety. So im just going to assume its my genetics. I had a pretty good upbringing and dont have any real reason to have social anxiety or any real reason why I like lots of isolation.... I just do.

 

[Pyropyro]

That's hideously expensive (almost half an average person's monthly salary here) but I want to take that test in the future.

 

[Ex-User (5841)]

if you look up "is introversion nature or nurture" you will get mixed results and i dont know why..we have evidence!

It's likely epigenetic, meaning that a specific gene or series of genes may be present, but may not be activated unless or until that person is exposed to certain environmental stimuli. There's also the problem of cognitive (Jungian) vs social introversion.

That's hideously expensive (almost half an average person's monthly salary here) but I want to take that test in the future.

I did 23&Me with a university discount for $69. The results were interesting, but the company has since run into some legal red tape regarding the general public's ability to interpret the results, and to be honest the testing is in its infancy. Look to take it in a few years.

 

[deadpixel]

That's hideously expensive (almost half an average person's monthly salary here) but I want to take that test in the future.

Its really cheap, I think its 99 dollars. They arent allowed to give speculative health reports anymore because the FDA doesnt think that they should, they only give ancestory reports now based on your DNA. They still sequence your dna and will allow you to download it I believe, once you have the information you can just plug in all of the information on your own, or there is another site that will analyze your data for you with the information from SNPedia.

 

[Nick]

I'm a TT with you on the rs35052149 single nucleotide protein.
I have no other RGS2 genes listed.

I've posted about 23andme 15 months ago...
http://intpforum.com/showthread.php?t=15100

for some odd reason our little INTP community here doesn't seem too active with researching and understanding their DNA through sequencing. Such a shame because it's relatively cheap and unlocks a whole new world of data for us to pour over.

 

[Red myst]

I'm a TT with you on the rs35052149 single nucleotide protein.
I have no other RGS2 genes listed.

I've posted about 23andme 15 months ago...
http://intpforum.com/showthread.php?t=15100

for some odd reason our little INTP community here doesn't seem too active with researching and understanding their DNA through sequencing. Such a shame because it's relatively cheap and unlocks a whole new world of data for us to pour over.

Too busy trying to figure out who the best fighter is or trying to understand wrestler girls popularity to be concerned with understanding DNA. Lol. I think it is something that has to "catch on". I'll bet that once it shows up on their radar there will be more interest. I think there should be a forum specifically for people who wish to discuss their DNA and observations about their tendencies as it relates to Jung functions, and in comparison to what society calls "introversion".

 

[deadpixel]

I'm a TT with you on the rs35052149 single nucleotide protein.
I have no other RGS2 genes listed.

I've posted about 23andme 15 months ago...
http://intpforum.com/showthread.php?t=15100

for some odd reason our little INTP community here doesn't seem too active with researching and understanding their DNA through sequencing. Such a shame because it's relatively cheap and unlocks a whole new world of data for us to pour over.

I have quite a good bit of social anxiety, I have a strong belief that this has something to do with rs4606.

How are you when it comes to social anxiety, Do you feel oddy uncomfortable around people for no apparent reason? im curious to know since this variant is absent with you.

 

[ApostateAbe]

I ordered a 23andMe kit just now. I will let you know when I get my results.

 

[deadpixel]

I ordered a 23andMe kit just now. I will let you know when I get my results.

Sounds good =)

 

[ApostateAbe]

I got my 23andMe kit today and put it back in the mail for processing. I am a little ticked because apparently the FDA recently cracked down on 23andMe providing medical information, so all I can get for my one hundred dollars is ancestry information.

 

[ApostateAbe]

I got my 23andMe data, and I searched for the gene. Here you go:

 

[Architect]

For both me (INTP) and my son (INTP) it's the same

Your data includes 3 SNPs on gene RGS2, which is on chromosome 1.
rs2746073 AT
rs35052149 TT
rs4606 CG

I'll check for my INFJ wife.

 

[Rook]

This thread has caught my interest....
We need more test data for a full comparison.
We may very well reach a viable conclusion in terms of genetic influence on one's personality.
Continue.

 

[Red myst]

For both me (INTP) and my son (INTP) it's the same

Your data includes 3 SNPs on gene RGS2, which is on chromosome 1.
rs2746073 AT
rs35052149 TT
rs4606 CG

I'll check for my INFJ wife.

I am familiar with your polls, do you think it is possible to set a thread up with a poll or survey so we could compile statistical data on this? I have my DNA results as well, but instead of listing my results in a post, I would rather just check off on a poll or survey which ones I have and which I don't, and monitor results as more people add to it. And as new genes are discovered that Meyer contribute to temperament, we could just add them to the survey and members could go and check their results and check off on the survey. Perhaps we will be able to see a pattern.

 

[Architect]

I am familiar with your polls, do you think it is possible to set a thread up with a poll or survey so we could compile statistical data on this?

Be my guest ...

My INFJ wife is exactly the same as myself (INTP) and my son (INTP)

Your data includes 3 SNPs on gene RGS2, which is on chromosome 1.
rs2746073 AT
rs35052149 TT
rs4606 CG

 

[deadpixel]

For both me (INTP) and my son (INTP) it's the same

Your data includes 3 SNPs on gene RGS2, which is on chromosome 1.
rs2746073 AT
rs35052149 TT
rs4606 CG

I'll check for my INFJ wife.

Very interesting architect, You and I have the same exact SNP's on RGS2 although the allele combinations are slightly different.
My dad is an INTP, he was an ISTP when he was younger but grew into INTP. I was also an ISTP when I was younger but have grown into an INTP over the last few years. He also has the same RGS2 SNP's as me so that is where I get that from. Im also an Enneagram type 5 with an even mix between 4wing and 6wing.

Im curious about your relationship with your wife, you mentioned that shes an INFJ. My girlfriend is an ISFJ, shes more S than N but only by a small percentage. If you dont mind me asking, what do you like about her and you guy's relationship?
Personally for me, as far as relationships go, this is the happiest I have ever been.
She adds a healthy balance in my life(her glass half empty way of thinking can be really good for my glass half full thinking)and I know that im always going to be ok and secure with this relationship, she makes sure that things happen that need to happen for the INTP that I am to exist in the society that we live in. This is my fourth serious relationship, the past 3 go like this.

1)Unhealthy ISFP(2 years exactly) - Very materialistic and irrational
2)Healthy ESFJ(2 years exactly) - Too outgoing for my comfort, this can be perceived as flirtation to other people, really its just an ESFJ being an ESFJ.
3)Unhealthy ESFP(2 years exactly) - Worst and lowest ive ever been in my life.
4)ISFJ(My current relationship, just passed the two year mark a couple of months ago and so far its looking like its going to last quite a while.) - Our disagreements stem from the communication difference between a thinker and feeler, which we are getting awesome at learning to neutralize disagreements and preventing them before they even happen through studying MBTI/Enneagram, and of course each other, shes a type 6.

 

[Architect]

My dad is an INTP, he was an ISTP when he was younger but grew into INTP. I was also an ISTP when I was younger but have grown into an INTP over the last few years.

No that's not true. You don't change type, period. You both are either ISTP (more statistically likely) or INTP (less statistically likely).

My brother is an ISTP (no question), he got

Your data includes 3 SNPs on gene RGS2, which is on chromosome 1.
rs2746073 TT
rs35052149 TT
rs4606 CC

Im curious about your relationship with your wife, you mentioned that shes an INFJ. My girlfriend is an ISFJ, shes more S than N but only by a small percentage.

My ISTP brother is married to an ISFJ. I'd halfway guess you really are an ISTP.

If you dont mind me asking, what do you like about her and you guy's relationship?.

I've written about it on the Ask Architect thread. She's maddening at times (so am I) but I couldn't be with anybody else. INTP-INFJ is called the "Golden Couple" for a reason; yes we're happy.

Check your type, I'd be willing to bet ISTP. Interesting that you share the same pattern as my brother above too.

 

[Base groove]

I'd halfway guess you really are an ISTP.

I have had this debate with cooper brown months ago when he first joined, wherein I called him an ISTP over and over.

If you could be so kind as to give a reason or two that applies directly to the information he has given us, I'd like to hear it... as I might have something to add.

 

[Red myst]

Be my guest ...

My INFJ wife is exactly the same as myself (INTP) and my son (INTP)

I have been contemplating how to structure this poll. I don't have enough information to know how to structure the selections. I need to know what other possible variations there could be before posting. (Example: do you have a, b, c, d, ect. in your genome stack and are you INFP, INTJ, INTP, ISFJ..... ect.)
I would like to contrast the selections with those known to be associated with extroversion.

I will just watch how this thread plays out and build something along the way. In the mean time I have my results imaged below.
They are exactly like yours. I have no idea how common these are. And I suspect that all this mostly has to do with social introversion and not the S/N or T/F dichotomies. But maybe through the lens of typology we may see a pattern of some sort. It will be interesting.

 

[Architect]

I have had this debate with cooper brown months ago when he first joined, wherein I called him an ISTP over and over.

If you could be so kind as to give a reason or two that applies directly to the information he has given us, I'd like to hear it... as I might have something to add.

One is that people don't change type. This is intrinsic to the theory and an observed fact. Behavior does change, and since people have difficulty distinguishing Type from behavior that obfuscates the issue.

In my experience going ISTP to INTP (in self typing) is unusual and not something INTP's do, but isn't uncommon for S types. The reason is as an Intuitive you know, practically from birth, that you are different from the norm because most frequently you are surrounded by S types, and you don't fit in*. On the other hand, since MBTI was invented by Intuitives I believe there is a bias in there which causes people to not want to be S types. Few people come to understand the CF's and since Sensors have Intuition in the inferior (an attractor) they usually later in life (as they integrated the tert and inferior) desire to be an intuitive of some type, so type themselves as such (also why they frequently take up religion so heavily).

Secondly the successful relationship with an ISFJ, which is the ideal partner type for an ISTP. In romantic relationships people ideally align on the first two letters and differ on the last two. It's too hard for an E and an I, likewise a S and a N to live together. They all speak different languages. But a relationship needs differentiation too so successful couples usually differ on the last two. Finally it would be a highly unusual INTP who got along with the tradition bound ISFJ, yet the ISTP loves them as they take care of all that in the relationship and "cover the bases".

Remember we necessarily use statistics to type, so he could be an unusual INTP but I would doubt it.

* I don't know when I met my first intuitive, maybe in my 20's. At any rate my self typing journey was INFJ-INTJ-INTP. This is a common track for INTP's, as first we (overly) identify with our inferior (Fe-INFJ), then our judging dominant (Ti-INTJ) then one hopes we figure out that we're an INTP.

 

[deadpixel]

One is that people don't change type. This is intrinsic to the theory and an observed fact. Behavior does change, and since people have difficulty distinguishing Type from behavior that obfuscates the issue.

In my experience going ISTP to INTP (in self typing) is unusual and not something INTP's do, but isn't uncommon for S types. The reason is as an Intuitive you know, practically from birth, that you are different from the norm because most frequently you are surrounded by S types, and you don't fit in*. On the other hand, since MBTI was invented by Intuitives I believe there is a bias in there which causes people to not want to be S types. Few people come to understand the CF's and since Sensors have Intuition in the inferior (an attractor) they usually later in life (as they integrated the tert and inferior) desire to be an intuitive of some type, so type themselves as such (also why they frequently take up religion so heavily).

Secondly the successful relationship with an ISFJ, which is the ideal partner type for an ISTP. In romantic relationships people ideally align on the first two letters and differ on the last two. It's too hard for an E and an I, likewise a S and a N to live together. They all speak different languages. But a relationship needs differentiation too so successful couples usually differ on the last two. Finally it would be a highly unusual INTP who got along with the tradition bound ISFJ, yet the ISTP loves them as they take care of all that in the relationship and "cover the bases".

Remember we necessarily use statistics to type, so he could be an unusual INTP but I would doubt it.

* I don't know when I met my first intuitive, maybe in my 20's. At any rate my self typing journey was INFJ-INTJ-INTP. This is a common track for INTP's, as first we (overly) identify with our inferior (Fe-INFJ), then our judging dominant (Ti-INTJ) then one hopes we figure out that we're an INTP.

All very interesting stuff architect, I dont think trying to type someone on a forum is a very easy or practical thing to do, for the best accuracy you would have to know them in person I would think.

I dont really think an ISTP has an advantage over an INTP and vice versa, I think that every personality type has something unique and different to offer than the next and we all have something to contribute. The notion that INTP's somehow have the upper hand is a conclusion that INTP's themselves have come to, Most people could care less about INTP's, and thats the truth. There is no common ground with an INTP for most types. Most people are not interested in the same things that an INTP are interested in.

Im not the type to say that im a certain way because I think it sounds better than what I really think I might be, that is a total waste of time. Whatever the case may be, I enjoy the conversations that I have with you guys on here and I like everyone here. Even though we have differences from time to time as do we all, they get brushed off rather quickly and all is good again.

By the way the ISFJ relationship isnt easy lol, its just the happiest I've been. The structured life works well for me, otherwise im much less likely to provide myself with one. There is nothing easy about a thinker trying to get a feeler to see their point of view and vice versa, two COMPLETELY different languages, Literally.

 

[scorpiomover]

Not really worth much, until we get at least 75% of the world tested and find that every single introvert has the gene, and every single extrovert doesn't.

On the flip side, if it is genetic, then it means that no matter how much you go out, you can't become any less introverted than you are. So if are not happy with your work, or your relationship, because you're not social enough to meet clients, you can now officially tell your g/f that it's your genes, and you might as well go and work as a bagger at Walmart, because that's all you can handle.

On the plus side, it means that your g/f can switch you from being a deep-thinking introvert to a party-animal extrovert, simply by slipping you a mickey of gene therapy retroviruses in your drinks. Ve haf vays of making you sociable!

 

[scorpiomover]

One is that people don't change type. This is intrinsic to the theory and an observed fact. Behavior does change, and since people have difficulty distinguishing Type from behavior that obfuscates the issue.

Yeah. But most people don't like their type. Type is about truth, and that means having to accept uncomfortable facts about oneself. When things change, people want to believe their type changed, because then they can pretend they've changed on a core level, and don't need to keep working on themselves.

In my experience going ISTP to INTP (in self typing) is unusual and not something INTP's do, but isn't uncommon for S types. The reason is as an Intuitive you know, practically from birth, that you are different from the norm because most frequently you are surrounded by S types, and you don't fit in*. On the other hand, since MBTI was invented by Intuitives I believe there is a bias in there which causes people to not want to be S types.

Yah. Dem intutives dem crazy mothers. Dey be thinking up nutso ideas all dem time.

The economy is shrinking. There's less jobs, and more importantly, less and less jobs that will support our lifestyles. We base everything off science now. So, you need to be more scientific to get a better job. But, we're not. So employers don't actually employ the people who ARE more scientific. They tend to use qualifications and resumes to estimate who is. So getting a job that meets your lifestyle expectations, requires you giving the IMPRESSION of being that scientific. So as long as you pretend, you're quids in. We don't see scientists in terms of their field, but in terms of their image, as being the guy who is a cut above the rest, who will think up ideas that the rest of us won't have. The majority think like Sensors. So, to present the idea that you're a special snowflake who should be paid more, you have to appear to be the guy who comes up new ideas that most of us won't think of. Hence, everyone wants to be typed as an Intuitive.

None of them actually want to BE an Intuitive, though, because Sensors won't understand what you're on about, and will assume you're talking rubbish. Intuitives with PhDs are ten-a-penny working in MacDonalds or in mental institutions. The very successful intuitives are usually Sensors, because their ideas are close enough to everyone else, that they can understand them. They just make them a teensy bit whacky to make them seem like they're original.

I don't know when I met my first intuitive, maybe in my 20's.

But, well, they're, EVERYWHERE! Can't miss them! Like they've got a sign on their heads. Seriously. Can't miss them.

 

[deadpixel]

I dont see anything wrong with ISTP's, I wish I were more ISTP than INTP. If I were more ISTP maybe id be more inclined to get out of the house and go do interesting things, then again just staying in my man cave for hours on end is fun enough.

 

[scorpiomover]

I dont see anything wrong with ISTP's, I wish I were more ISTP than INTP. If I were more ISTP maybe id be more inclined to get out of the house and go do interesting things, then again just staying in my man cave for hours on end is fun enough.

Introversion is far more likely a cause for staying in, than intution. Take a look at ENTPs. Always out the house. They roam around the world to an incredible extent. They'd go to Germany for the weekend, just because they've never been there before.

 

[deadpixel]

Introversion is far more likely a cause for staying in, than intution. Take a look at ENTPs. Always out the house. They roam around the world to an incredible extent. They'd go to Germany for the weekend, just because they've never been there before.

You are right, I guess I forgot to mention what it is that I do while I'm inside. I'm playing with computers, tinkering, reading, and watching brain stimulating documentaries.

An istp is more likely going to want to get out as they seek external stimulation from the outside world through activities like sports, skydiving, base jumping, racing, thrill seeking, the gym pumping iron to work on their physique, etc etc. Which istp's are supposedly infamous for. None of which I do, never have, don't have an interest to, and never will as far as I can tell.

 

[Base groove]

they seek external stimulation from the outside world through activities like sports, skydiving, base jumping, racing, thrill seeking, the gym pumping iron to work on their physique, etc etc. Which istp's are supposedly infamous for..

I disagree. I think they are infamous for staying home and playing games and learning as much as they can then still beating you in a fight you started.

You're talking more about Se and Ne dominants.

 

[deadpixel]

I disagree. I think they are infamous for staying home and playing games and learning as much as they can then still beating you in a fight you started.

You're talking more about Se and Ne dominants.

The only reason I mention that is because every description I read about ISTP, they all mention high energy activities, thrills, external stimuli. You dont see any of that when you read material about INTP.