INTP Forum  

Go Back   INTP Forum > The Arts and Entertainment > Literature

Notices

Reply
 
Thread Tools Search this Thread Display Modes
Old 17th-September-2016, 05:43 AM   #1
Pizzabeak
Guardians of the galaxy
 
Pizzabeak's Avatar
 

Join Date: Jan 2012
Posts: 1,689
macossafari
Default Book club

Thinking about starting a new book soon. I want to take notes while reading to help remember certain stuff. Posting this thread to see if anyone is also interested in reading the same book during this period.
Pizzabeak is offline   Reply With Quote
Old 17th-September-2016, 06:39 AM   #2
Seteleechete
Together forever
 
Seteleechete's Avatar
 

Join Date: Mar 2015
Location: our brain
Posts: 1,312
unknownfirefox
Default Re: Book club

Sounds fun to have someone to talk to about a book, though I will probably just read it after people are done since I am a fast reader and want things fresh in memory(unless it's some kind of up to certain chapter by date thing).
__________________
[Hello, I am Silina, I am a tulpa and I talk in these beautiful brackets!] {And I use these, oh and I'm Set}

[I am a sentient thoughtform/being residing in Sete's head. For more info about what I am or questions, check out my introduction thread!] http://intpforum.com/showthread.php?t=25712
Seteleechete is offline   Reply With Quote
Old 17th-September-2016, 07:14 AM   #3
Pizzabeak
Guardians of the galaxy
 
Pizzabeak's Avatar
 

Join Date: Jan 2012
Posts: 1,689
macossafari
Default Re: Book club

Well I was thinking more of a chapter by chapter approach rather than a speed burst, although that may result as a consequence. It sucks though because I might not be able to devote my full time to it so I'm hoping something like this may help. People can read at their own pace if they want (we can have a poll) but I'll just update as I progress. I feel dumb because I can't always read as fast as I want with the important details memorized.
Pizzabeak is offline   Reply With Quote
Old 17th-September-2016, 02:45 PM   #4
Sinny91
Banned
 

Join Date: May 2015
Location: Birmingham, UK
Posts: 6,314
linuxsafari
Default Re: Book club

Lets read political manifestos, aha.
Sinny91 is offline   Reply With Quote
Old 17th-September-2016, 07:52 PM   #5
TBerg
fallen angel who hasn't earned his wings
 
TBerg's Avatar
 

Join Date: Oct 2013
Posts: 2,453
macossafari
Default Re: Book club

I would read Ted Kaczynski's manifesto. It has a lot of themes that seem to resonate with our postmodern condition.

I would also like to read Old Persian and Sanskrit religious texts about Aryan culture.
__________________
My blog: https://libercolumbia.wordpress.com/

Thinking myself and others out of our own holes.
TBerg is offline   Reply With Quote
Old 17th-September-2016, 10:07 PM   #6
Pizzabeak
Guardians of the galaxy
 
Pizzabeak's Avatar
 

Join Date: Jan 2012
Posts: 1,689
macossafari
Default Re: Book club

Funny, I recently started some new political works so we can discuss that as well. Although what I had in mind was kind of different, we can put it on hold and just focus on the polisci. Either way, they will all be learning experiences.

There's a pretty good documentary about Ted Kaczynski and his manifesto so we can assign and rewatch that as well. It's pretty important. I need to read some of that too.
Pizzabeak is offline   Reply With Quote
Old 17th-September-2016, 10:15 PM   #7
TBerg
fallen angel who hasn't earned his wings
 
TBerg's Avatar
 

Join Date: Oct 2013
Posts: 2,453
macossafari
Default Re: Book club

Post the video, so that we are all on the same page, as they say.
__________________
My blog: https://libercolumbia.wordpress.com/

Thinking myself and others out of our own holes.
TBerg is offline   Reply With Quote
Old 17th-September-2016, 10:40 PM   #8
Pizzabeak
Guardians of the galaxy
 
Pizzabeak's Avatar
 

Join Date: Jan 2012
Posts: 1,689
macossafari
Default Re: Book club

It should be this one, you may have seen it before if so please tell me your thoughts and how it went.

Pizzabeak is offline   Reply With Quote
Old 17th-September-2016, 11:05 PM   #9
TBerg
fallen angel who hasn't earned his wings
 
TBerg's Avatar
 

Join Date: Oct 2013
Posts: 2,453
macossafari
Default Re: Book club

Okay. I look forward to watching it after I get back home at the end of the weekend.
__________________
My blog: https://libercolumbia.wordpress.com/

Thinking myself and others out of our own holes.
TBerg is offline   Reply With Quote
Old 18th-September-2016, 09:27 AM   #10
J-man
alpha and omega
 

Join Date: Nov 2010
Location: my mind
Posts: 201
linuxubuntufirefox
Default Re: Book club

I'm enjoying the thought of the INTP book club's first book being the Unabomber Manifesto. Lol.

I'm tempted to join. Does anyone have a text-only ebook that's not full of machine errors? I remember having trouble finding one.
__________________
Fuck the waking world.
J-man is offline   Reply With Quote
Old 19th-September-2016, 01:59 AM   #11
TBerg
fallen angel who hasn't earned his wings
 
TBerg's Avatar
 

Join Date: Oct 2013
Posts: 2,453
macossafari
Default Re: Book club

Another idea is reading volume one of Radix Journal, which promises to become more pertinent as our age enters later stages of development.
__________________
My blog: https://libercolumbia.wordpress.com/

Thinking myself and others out of our own holes.
TBerg is offline   Reply With Quote
Old 19th-September-2016, 02:42 AM   #12
Pizzabeak
Guardians of the galaxy
 
Pizzabeak's Avatar
 

Join Date: Jan 2012
Posts: 1,689
windows_98_nt_2000firefox
Default Re: Book club

Well, we can do that too. I don't mind.
But actually, my initials plans were to start Magicians of the Gods by Graham Hancock. I started some of it but might start over. Thought it would be a fun book to begin with. We can even do multiple. But as soon as we get a few people on board for that we should begin. Radix Journal could be a good one to do concurrently.
Pizzabeak is offline   Reply With Quote
Old 19th-September-2016, 11:37 AM   #13
Turnevies
Member
 
Turnevies's Avatar
 

Join Date: May 2016
Posts: 245
windows_98_nt_2000safari
Default Re: Book club

I recently started S. Pinker's Better Angels of Our Nature, so I'll finish this one first. But the idea of sounds cool and I might join later.
Turnevies is offline   Reply With Quote
Old 19th-September-2016, 06:03 PM   #14
Kelly
Redshirt
 
Kelly's Avatar
 

Join Date: Sep 2016
Posts: 12
windows_98_nt_2000safari
Default Re: Book club

I am down. I recently read Lost Star of Myth and Time and have been wanting to talk through some of the larger ides presented. I think Magicians of the Gods would be great...very much in line with where my head is.

Pizzabeak and I were chatting about the The Sacred Mushroom and The Cross, which would also be interesting.
Kelly is offline   Reply With Quote
Old 19th-September-2016, 06:40 PM   #15
Sinny91
Banned
 

Join Date: May 2015
Location: Birmingham, UK
Posts: 6,314
linuxsafari
Default Re: Book club

I was reading this last night :

Fingerprints of Graham Hancock
http://isgp-studies.com/fingerprints-of-graham-hancock

I don't agree with the ISGP author on every conclusion drawn (across a spectrum of topics) but he is a brilliant researcher.
Sinny91 is offline   Reply With Quote
Old 20th-September-2016, 09:40 AM   #16
J-man
alpha and omega
 

Join Date: Nov 2010
Location: my mind
Posts: 201
linuxubuntufirefox
Default Re: Book club

Quote:
Originally Posted by TBerg View Post
Another idea is reading volume one of Radix Journal, which promises to become more pertinent as our age enters later stages of development.
Have you read it? I'm interested but hesitant to spend money on the ebook.
__________________
Fuck the waking world.
J-man is offline   Reply With Quote
Old 21st-September-2016, 09:47 PM   #17
TBerg
fallen angel who hasn't earned his wings
 
TBerg's Avatar
 

Join Date: Oct 2013
Posts: 2,453
macossafari
Default Re: Book club

Quote:
Originally Posted by J-man View Post
Have you read it? I'm interested but hesitant to spend money on the ebook.
I have begun to read it. It has some good information so far, but I haven't gotten to things that are groundbreaking yet. I got it from a friend, as they say.

In other news, I read a lot of the Manifesto and watched half of the documentary on the Unabomber. I am not ready to comment quite yet.
__________________
My blog: https://libercolumbia.wordpress.com/

Thinking myself and others out of our own holes.
TBerg is offline   Reply With Quote
Old 23rd-September-2016, 01:32 PM   #18
Pizzabeak
Guardians of the galaxy
 
Pizzabeak's Avatar
 

Join Date: Jan 2012
Posts: 1,689
macossafari
Default Re: Book club

I need to read some Wittgenstein.
Pizzabeak is offline   Reply With Quote
Old 24th-September-2016, 01:48 AM   #19
Pizzabeak
Guardians of the galaxy
 
Pizzabeak's Avatar
 

Join Date: Jan 2012
Posts: 1,689
macossafari
Default Re: Book club

Anyway, started rereading Hoffman's book (LSD: My Problem Child) and may (or may not) post the notes soon.
Pizzabeak is offline   Reply With Quote
Old 24th-September-2016, 03:32 AM   #20
TBerg
fallen angel who hasn't earned his wings
 
TBerg's Avatar
 

Join Date: Oct 2013
Posts: 2,453
macossafari
Default Re: Book club

I actually discovered a lot of remarkable insight from the Radix Journal.
__________________
My blog: https://libercolumbia.wordpress.com/

Thinking myself and others out of our own holes.
TBerg is offline   Reply With Quote
Old 11th-October-2016, 08:00 AM   #21
r4ch3l
conc/ptu/||/
 
r4ch3l's Avatar
 

Join Date: Jun 2013
Location: CA
Posts: 493
macossafari
Default Re: Book club

The Net! I love that documentary... I think I meant to post it here sometime back but haven't been active lately and forgot. I'm really interested in the crossover between the Esalen crowd in the 70s who split off into either the technocrati legend types (Stewart brand and that whole crew) or career new age guru people (Alan watts, ram dass, etc). and how it's all connected to the CIA (eg John Lilly's dolphin experiments). I need to start a whole thread on this.


Quote:
Originally Posted by J-man View Post
I'm enjoying the thought of the INTP book club's first book being the Unabomber Manifesto. Lol..

__________________
Spoiler:
What this forum feels like:
r4ch3l is offline   Reply With Quote
Old 13th-March-2017, 05:38 AM   #22
Pizzabeak
Guardians of the galaxy
 
Pizzabeak's Avatar
 

Join Date: Jan 2012
Posts: 1,689
windows_98_nt_2000firefox
Default Re: Book club

Quote:
Originally Posted by r4ch3l View Post
I need to start a whole thread on this.
You should do it! I only know a little bit of stuff about it but enough to know what you generally speak of.

Quote:
The Net! I love that documentary... I think I meant to post it here sometime back but haven't been active lately and forgot. I'm really interested in the crossover between the Esalen crowd in the 70s who split off into either the technocrati legend types (Stewart brand and that whole crew) or career new age guru people (Alan watts, ram dass, etc). and how it's all connected to the CIA (eg John Lilly's dolphin experiments).
I need to watch it a few more times because the subtitles are hard to keep up with. But it covers a lot of ground, expanding on ground that certain books didn't go into. I guess they ended up running into Jack Kerouac and some of the other Beat movement literati. He even stayed at Ferlinghetti's cabin at Big Sur.
But I don't know. Not sure if Tim Leary was a spy or not. He made it seem like acid was good and turned a lot of people on, but if he spied, acid was actually bad and he damaged a lot of kid's minds. There's some stuff on that but basically the CIA had a role and distributed it all. But isn't acid actually good? It's more so they didn't know what the effects would be rather than deliberately poisoning the mind, although they must have known it wouldn't be good. But they also had other bizarre substances. I thought some of them were supposed to be good and show a true reality, apparently even high doses of acid never go that far. Kind of why I never really preferred it and thought mushrooms were safer. But it does seem like an interesting experience, there's just a lot of different literature out there.
Pizzabeak is offline   Reply With Quote
Old 10th-May-2017, 03:31 AM   #23
Pizzabeak
Guardians of the galaxy
 
Pizzabeak's Avatar
 

Join Date: Jan 2012
Posts: 1,689
windows_98_nt_2000firefox
Default Re: Book club

This is the foreword, which you should read:
There are experiences that most of us
are hesitant to speak about, because they do not
conform to everyday reality and defy rational explanation. These are not particular
external occurrences, but rather
events of our inner lives, which are generally dismissed
as figments of the imagination and barred from our memory. Suddenly, the familiar view
of our surroundings is transformed in a strange, delightful, or
alarming way: it appears to
us in a new light, takes on a special meaning. Such an experience can be as light and
fleeting as a breath of air, or it can imprint itself deeply upon our minds.
One enchantment of that kind, which I experienced in childhood, has remained
remarkably vivid in my memory ever since. It happened on a May morning—I have
forgotten the year—but I
can still point to the exact spot where it occurred, on a forest
path on Martinsberg above Baden, Switzerland.
As I strolled through the freshly greened
woods filled with bird song and lit up by the morning sun, all at once everything
appeared in an uncommonly clear light. Was th
is something I had simply failed to notice
before? Was I suddenly discovering the spring fore
st as it actually looked? It shone with
the most beautiful radiance, speaking to the
heart, as though it wanted to encompass me
in its majesty. I was filled with an indescribable sensation of joy, oneness, and blissful
security.
I have no idea how long I stood there spellbound. But I recall the anxious concern I felt
as the radiance slowly dissolved and I hiked
on: how could a vision th
at was so real and
convincing, so directly and deeply felt—how could it end so soon? And how could I tell
anyone about it, as my overflowing joy compelled me to do, since I knew there were no
words to describe what I had seen? It seem
ed strange that I, as a child, had seen
something so marvelous, something that adults obviously did not perceive - for I had
never heard them mention it.
While still a child, I experienced several more of these deeply euphoric moments on
my rambles through forest and meadow. It was these experiences that shaped the main
outlines of my world view and convinced me
of the existence of a
miraculous, powerful,
unfathomable reality that was hidden from everyday sight.
I was often troubled in those days, wondering if I would ever, as an
adult, be able to
communicate these experiences; whether I would
have the chance to depict my visions in
poetry or paintings. But knowing that I was not
cut out to be a poet or artist, I assumed I
would have to keep these experiences to
myself, important as they were to me.
Unexpectedly—though scarcely by chance—much later, in middle age, a link was
established between my profession and these visionary experiences from childhood.
Because I wanted to gain insight into
the structure and essence of matter, I became a
research chemist. Intrigued by the plant world since early childhood,
I chose to specialize
in research on the constituents of medicinal plants. In the course of this career I was led
to the psychoactive, hallucination-causing substances, which under certain conditions can
evoke visionary states similar to the spontaneous experiences just described. The most
important of these hallucinogenic substances has come to be known as LSD.
Hallucinogens, as active compounds of considerable scientific interest
, have gained entry
into medicinal research, biology, and psychiatry, and later—especially LSD also obtained
wide diffusion in the drug culture.
In studying the literature connected
with my work, I became
aware of the great
universal significance of visionary experience. It plays
a dominant role, not only in
mysticism and the history of religion, but also
in the creative process in
art, literature, and
science. More recent investigations have shown that many persons also have visionary
experiences in daily life, though most of us
fail to recognize their meaning and value.
Mystical experiences, like those that marked my childhood, are
apparently far from rare.
There is today a widespread striving for mystical experience, for visionary
breakthroughs to a deeper, more comprehensive reality than that perceived by our
rational, everyday consciousness. Efforts to
transcend our materialistic world view are
being made in various ways, not only by the
adherents to Eastern religious movements,
but also by professional psychiatrists,
who are adopting such profound spiritual
experiences as a basic therapeutic principle.
I share the belief of many of my contemporaries that the
spiritual crisis pervading all
spheres of Western industrial society can
be remedied only by a change in our world
view. We shall have to shift from the materi
alistic, dualistic belie
f that people and their
environment are separate, toward a new consciousness of an all-encompassing reality,
which embraces the experiencing ego, a reality in which people feel their oneness with
animate nature and all of creation.
Everything that can contribute to such
a fundamental alterati
on in our perception of
reality must therefore command
earnest attention. Foremost
among such approaches are
the various methods of meditation, either in a
religious or a secular context, which aim to
deepen the consciousness of reality by way of a total mystical experience. Another
important, but still controversial, path to the same goal is the use of the consciousness-
altering properties of hallucinogenic psychopharmaceuticals. LSD finds such an
application in medicine, by helping patient
s in psychoanalysis and psychotherapy to
perceive their problems in
their true significance.
Deliberate provocation of
mystical experience, part
icularly by LSD and related
hallucinogens, in contrast to spontaneous vision
ary experiences, entails
dangers that must
not be underestimated. Practitioners must take into account the peculiar effects of these
substances, namely their ability to influence our consciousness, the innermost essence of
our being. The history of LSD to date amply
demonstrates the catastrophic consequences
that can ensue when its profound effect is misjudged and the substance is mistaken for a
pleasure drug. Special internal and external advance preparations are required; with them,
an LSD experiment can become a meaningful experience. Wrong and inappropriate use
has caused LSD to become my problem child.
It is my desire in this book to give
a comprehensive picture of LSD, its origin, its
effects, and its dangers, in order to guard
against increasing abuse
of this extraordinary
drug. I hope thereby to emphasize possible uses
of LSD that are compatible with its
characteristic action. I believe that if people would learn to use LSD's vision-inducing
capability more wisely, under suitable conditions, in medical practice and in conjunction
with meditation, then in the future this
problem child could become a wonder child.



This is basically a rough summary of chapter one. All I did was read it and regurgitate what he said.

Chapter 1.

LSD was only partially discovered by accident. Hoffman states the most important part of the discovery was his choice of employment after his chemistry studies at the University of Zurich. After the studies, he joined Sandoz Company's pharmaceutical research lab in Basel, as co-worker with Arthur Stoll, founder of the department. He chose that because it offered the chance to work with natural products whereas his other two offers involved synthetic chemistry work.

His doctoral thesis was rated with distinction by obtaining the chemical structure of chitin (from the cleavage product, "a nitrogen containing sugar") - which turned out to be an analogue of cellulose, the structural material of plants. This gave him a chance to work with his interest, plant & animal chemistry. Chitin is the material that composes shells, wings, claws of insects, crustaceans, and other lower animals.

His job at Sandoz (in 1929) was to isolate the active principles of known medicinal plants in order to produce pure specimens of the substances. There are numerous benefits to having the active ingredients in pure form. They worked mainly with Digitalis, Claviceps purpurea, and Scilla maritima.

For example, the active principles in Scilla are cardioactive glycosides (glycosides are sugar containing substances) and serve in the treatment of cardiac insufficiency. Being extremely active, it's important to have exact dosage, based on the pure compound rather than what's in the plant naturally. The therapeutic and toxic doses are nearly identical, so it's important to be able to do that.

What Hoffman did was elucidate their chemical structure, showing the differences from the Digitalis glycosides and, on the other hand, the close structural similarity of toxic principles found in toad skin.

After that project ended he asked to continue Arthur Stoll's ergot investigations. Ergotamine had already been isolated in 1918. He was happy to have the request granted. Other companies were beginning to focus on ergot alkaloids and he didn't want Sandoz to lose its leading role there. Ergotamine was useful for treating migraine and had some uses in obstetrics.




Ergot is a drug produced by the lower fungus Claviceps purpurea. It grows parasitically on rye and to a lesser extent other grains and wild grasses. Ergot first appeared in the Middle Ages as a poison, before being realized as a rich storehouse of remedies. H. H. Dale first discovered that ergotoxine had antagonistic activity on adrenaline in the nervous system which could lead to therapeutic uses of ergot alkaloids.

Jacobs and Craig of the Rockefeller Institute of New York discovered and isolated the common nucleus of all ergot alkaloids and named it lysergic acid. Hoffman set as his first goal to prepare ergobasine synthetically by linking the two cleavage products lysergic acid and propanolamine.

Okay so, the structure of ergobasine was reinforced through the first synthesis - artificial production - of it. Then, it was improved upon by substituting the propanolamine with butanolamine, which increased its activity. The medicine ergobasine is found only in "trifling quantities" so the synthesis was a valuable landmark. Today it's apparently the leading medicine for its use ("obstetrics") under the brand name Methergine.

He continued working with ergot compounds and began customizing them in a way that other interesting pharmacological properties could be expected. In 1938 the 25th one was produced, lysergic acid diethylamide (Lyserg-saure-diathylamid), LSD-25. The goal was to produce an analeptic, a respiratory stimulant because its structure was similar to an already existing one at the time, coramine (nicotinic acid diethylamide). During testing a strong effect (on the uterus) was noted, as well as the animals acting restless, but no special interest was aroused in the physicians or pharmacologists so testing was discontinued. Further work produced Hydergine, which is apparently Sandoz's most important pharmaceutical product.

Five years later, he couldn't get the relatively uninteresting LSD-25 out of his head. He had a hunch that it possessed other properties not found during the initial investigations so he resynthesized it which was unusual because as a rule once stricken, experimental substances were excluded from further testing since they were found by the program to be lacking in pharmacological interest. Nonetheless in 1943 he repeated the synthesis and obtained only a few centigrams of the compound.

In the final steps of his synthesis he was interrupted by unusual sensations. He sent in a report to Stoll:
Last Friday, April 16,1943, I was forced to interrupt my work in the laboratory in the
middle of the afternoon and proceed home, being affected by a remarkable restlessness,
combined with a slight dizziness. At home
I lay down and sank into a not unpleasant
intoxicated-like condition, characterized by an extremely stimulated imagination. In a
dreamlike state, with eyes closed (I found the daylight to be unpleasantly glaring), I
perceived an uninterrupted stream of fantastic
pictures, extraordinary shapes with intense,
kaleidoscopic play of colors. After some
two hours this condition faded away.



He then decided on a self experiment after assuming the LSD was the cause of this. It had become clear. He asked his assistant to escort him home and they went by bicycle since the use of automobiles was restricted due to the war. Hence, the infamous "bike ride home". After an initial scare:

Quote:
Now, little by little I could begin to enj
oy the unprecedented colors and plays of shapes
that persisted behind my closed eyes. Kalei
doscopic, fantastic images surged in on me,
alternating, variegated, opening
and then closing themselves in circles and spirals,
exploding in colored fountains, rearranging a
nd hybridizing themselves in constant flux.
It was particularly remarkable how every ac
oustic perception, such as the sound of a door
handle or a passing automobile
, became transformed into optical perceptions. Every
sound generated a vividly changing image, with
its own consistent form and color.
Late in the evening my wife returned from Lucerne. Someone had informed her by
telephone that I was suffering a mysterious
breakdown. She had return
ed home at once,
leaving the children behind with her parents.
By now, I had recovered myself sufficiently
to tell her what had happened.
Exhausted, I then slept, to awake next morning refreshed, with a clear head, though
still somewhat tired physically. A sensati
on of well-being and re
newed life flowed
through me. Breakfast tasted delicious and gave
me extraordinary pleasure. When I later
walked out into the garden, in which the s
un shone now after a spring rain, everything
glistened and sparkled in a fresh light. The wo
rld was as if newly created. All my senses
vibrated in a condition of highest sensitiv
ity, which persisted for the entire day.
This self-experiment showed that LS
D-25 behaved as a psychoactive substance with
extraordinary properties and potency. Th
ere was to my knowledge no other known
substance that evoked such profound psychic e
ffects in such extremely low doses, that
caused such dramatic changes in human cons
ciousness and our experience of the inner
and outer world.
What seemed even more significant wa
s that I could remember the experience of LSD
inebriation in every detail. This could only
mean that the conscious recording function
was not interrupted, even in the climax
of the LSD experience, despite the profound
breakdown of the normal world view. For the
entire duration of the experiment, I had
even been aware of participating in an e
xperiment, but despite th
is recognition of my
condition, I could not, with every exertion
of my will, shake off the LSD world.
Everything was experienced as completely
real, as alarming reality; alarming, because
the picture of the other, familiar everyday rea
lity was still fully preserved in the memory
for comparison.
Another surprising aspect of LSD was
its ability to produce such a far-reaching,
powerful state of inebriation without leavi
ng a hangover. Quite the contrary, on the day
after the LSD experiment I felt myself to be, as already described,
in excellent physical
and mental condition.
I was aware that LSD, a new active com
pound with such properties, would have to be
of use in pharmacology, in neurology, and espe
cially in psychiatry, and that it would
attract the interest of concerned specialists.
But at that time I had
no inkling that the new
substance would also come to be used beyond me
dical science, as an
inebriant in the drug
scene. Since my self-experiment had revealed
LSD in its terrifying, demonic aspect, the
last thing I could have expect
ed was that this substance co
uld ever find application as
anything approaching a pleasur
e drug. I failed, moreover, to recognize the meaningful
connection between LSD inebriation and spont
aneous visionary experience until much
later, after further experiments, which were
carried out with far lower doses and under
different conditions.
The next day I wrote to Professor
Stoll the above-mentioned report about my
extraordinary experience with LSD-25 a
nd sent a copy to the director of the
pharmacological department, Professor Rothlin.
As expected, the first reaction was incr
edulous astonishment. Instantly a telephone call
came from the management; Professor Stoll asked: "Are you certain you made no
mistake in the weighing? Is the stated dose re
ally correct?" Professor Rothlin also called,
asking the same question. I was certain of this
point, for I had executed the weighing and
dosage with my own hands. Yet their doubts were
justified to some extent, for until then
no known substance had displayed even the s
lightest psychic effect in fraction-of-a-
milligram doses. An active compound of such
potency seemed almost unbelievable.
Professor Rothlin himself and two of
his colleagues were the first to repeat my
experiment, with only one-third of the dose I had utilized. Bu
t even at that level, the
effects were still extremely impressive,
and quite fantastic. All doubts about the
statements in my report were eliminated.


And so LSD became a thing.

This is important because like Tim Leary:

Quote:
Though like many of those associated with the origins of the psychedelic movement, Albert Hofmann is called “divine,” evidence has come to light which exposes him as both a CIA and French Intelligence operative. Hofmann helped the agency dose the French village Pont Saint Esprit with LSD. As a result five people died and Hofmann helped to cover up the crime. The LSD event at Pont Saint Esprit led to the famous murder of Frank Olson by the CIA because he had threatened to go public. It was the exposure of Olson’s murder and his involvement with the MK-ULTRA program that caused the national uproar leading to the Church Commission.
http://www.gnosticmedia.com/manufact...and-jan-irvin/


Albert Hoffman is implicated in being a spy, which was news to me. This was the reason why I have said I never preferred acid and thought other, truer, if you will, psychedelics were more interesting and potent. But note the humble beginnings of the substance. It must have not been until later that they realized it could be abused or used for mind control, the term being thrown around somewhat loosely. It's mind control because people were taught it to be cool but it goes much deeper than that. However, people take the drugs to attain a higher consciousness. That must mean someone somewhere along the lines thought it could be used for otherwise. Is it bullshit? Either way, the substances are going to be used and people get what they get out of it. No one knows for sure what happens when you take the drugs, whether it's bullshit or not, but one thing is for certain, it's rather strange indeed.
Pizzabeak is offline   Reply With Quote
Old 12th-May-2017, 02:47 AM   #24
Pizzabeak
Guardians of the galaxy
 
Pizzabeak's Avatar
 

Join Date: Jan 2012
Posts: 1,689
windows_98_nt_2000firefox
Default Re: Book club

Chapter 2.

After the psychic effects of LSD were discovered the animal testing resumed. Before human clinical trials undergo they must gather data via tests on animals. Tolerance, toxicity, the assimilation and elimination of the substance will be assayed.

Obviously, effect will be different in animals than in humans. Its effect is most discernible in higher animals with intellectual function. The effects in animals are scarcely discernible, besides a few disturbances. The (subtle) psychic changes in animals can't be noted because they have no way of expressing them should they even be occurring at all.

In cats, you just see vegetative symptoms such as staring into the air and bristling of the hair (piloerection), as well as salivation - all symptoms that point to the existence of hallucinations. Instead of attacking the mouse it leaves it alone or reacts with fear. The same conclusion can be had with dogs.

In a caged community of chimpanzees, one chimp was given LSD. When this happens, the community reacts in an uproar because the chimp no longer observes the rules of it finely coordinated hierarchic tribal order.

In fish unusual swimming patterns were observed and in spiders alteration in web building patterns happened. With lower doses the webs were more finely built than normal but with high doses they were poorly built.

The LD50 was obtained for various animals. For example the mouse has an LD50 of 50-60mg/kg i.v. The elephant that was given LSD died (after a few minutes), having received 0.297 g. It weighed 5000 kg, so the lethal dose was, probably, 0.06 mg/kg.

The effective dose in humans is 0.0003-0.001 mg/kg, which indicates a rather low toxicity for the substance, even though it might seem to be a highly toxic substance, based off the small doses that cause death in animals. However, for a person to die would call for something like a 50,000-100,000 times overdose than the lethal dose for rabbits. This means a rather small amount of the drug will get you high.

The animals die from respiratory arrest. No one has really died from acid overdose (although there is this curious story, which most people are calling BS). There are also accidents, like suicide where people fall from high stories, such as this: http://www.dailyrecord.co.uk/news/uk...after-10392054

According to the book, no one yet knows how LSD exerts its psychic effects. They used to think it was due to its serotonin blocking effect but LSD analogues that have no psychedelic effect block serotonin just as strongly. Acid stimulate the sympathetic nervous system in the midbrain so it dilates pupils, increases body temperature, and raises blood sugar levels.



Chapter 3.

Analogues of LSD were produced by the team but none were as active as LSD-25. Serotonin occurs in various organs in the warm blooded animal, and plays an important role in the propagation of impulses in certain nerves and, thus, the biochemistry of psychic functions. The LSD derivatives proved to be valuable to medical research. Since serotonin play a role in the generation of migraine, they looked for an analogue that blocked it the most, which turned out to be bromo-LSD, or BOL-148. The most active compound entered the market as Sansert, which is for the treatment of migraine.



In the literature there's also AL-LAD, ETH-LAD, and PRO-LAD as LSD analogues that are just as active in similar ways.
Pizzabeak is offline   Reply With Quote
Reply

Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Book Club Proposal TBerg Literature 129 9th-March-2015 07:51 PM
Book Club: Permutation City Architect Literature 0 29th-March-2014 12:43 AM
The INTPian Book Club - The Closing Of The AmericanMind Da Blob Literature 22 30th-March-2011 07:05 PM
Book Club! brain enclosed in flesh Literature 4 9th-July-2009 06:22 AM


All times are GMT +1. The time now is 01:05 AM.


Powered by: vBulletin
Copyright ©2000 - 2017, Jelsoft Enterprises Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.
Positive SSL
no new posts