If you have patience and like atmospheric games, music and literature, you should try to hunt down a game called "Pathologic", developed by a Russian studio called Icepick Lodge.
The graphics look like something out from a late Playstation or early Playstation 2 era game, but it doesn't matter, because the game is a brilliant exercise in atmosphere.
The same studio also developed a game called "Tension", in Russian, but it's going to be released in the States as "The Void". Check some videos on youtube as Tension/The Void... I really have no idea what the game is about, but the videos look fun.
What we need is more original games, I'm really growing tired of the same derivative games time and again. Right now the only game I've been playing for a while is Far Cry 2... I know many people didn't like it, but I actually like it for the reasons they didn't... plus, I love African landscapes and I find the whole mercenary idea kinda romantic in its raw savagery.
I have also been waiting for a game called "limbo" for quite some time, but everything seems to point it has gone vaporware: